RESUMEN Introducción: No todos los especialistas en formación en Anestesiología y Reanimación revelan una actuación eficiente en la atención al paciente en shock. Objetivo: Exponer elementos relacionados con un sistema de talleres docentes para potenciar la preparación del especialista en formación en Anestesiología para la atención médica integral al paciente en shock. Material y método: Se realizó un estudio prospectivo con enfoque cualitativo que tiene en cuenta la sistematización de los referentes teóricos esenciales que posibilitan la satisfacción del objetivo declarado. (...) Resultados: se definió operacionalmente la categoría preparación del especialista en formación en Anestesiología y Reanimación para la atención médica integral al paciente en shock, y se diseñó un sistema de talleres docentes que puede guiar el trabajo metodológico del colectivo de profesores para la consecución de este propósito. Discusión: Se propuso una modelación didáctica del proceso de preparación de este especialista en formación, que puede tributar a una transformación cualitativamente superior del proceso de formación, y a la profesionalización pedagógica del docente. ABSTRACT Introduction: Not all the specialists in formation in Anesthesiology and Revival reveal an efficient performance in the attention to the patient in shock. Objective: To exhibit elements related to a system of teaching workshops to promote the preparation of the specialist in formation in Anesthesiology for the integral medical attention to the patient in shock. Material and method: A pilot study was carried out with qualitative approach that bears in mind the systematization of the essential theoretical basis that make possible the satisfaction of the declared objective. Results: it was defined operationally the category preparation of the specialist in formation in Anesthesiology and Revival for the integral medical attention to the patient in shock, and it was designed a system of teaching workshops that can guide the methodological work of the teachers' group for the attainment of this intention. Discussion: There was proposed a didactic modeling of the process of preparation of this specialist in formation, which it can contribute to a qualitatively top transformation of the process of formation, and to the pedagogic professionalization of the teacher. (shrink)

Negar el libre albedrío implica que el ser humano no es libre por naturaleza, sino que puede llegar a serlo mediante un uso adecuado de su inteligencia; libertad que solo la consiguen los “sabios”. Por eso, cuando Spinoza entiende la democracia como la forma de gobierno que mejor defiende la libertad, esto vale para los “sabios”, pero no para el vulgo, que solo mediante el miedo y la esperanza es conducido a obrar según los dictados de la razón. ¿No será (...) esta indeseable consecuencia la que le impidió terminar su Tratado Político, precisamente cuando se aprestaba a estudiar la democracia? (shrink)

En este artículo se estudia el papel jugado por diferentes órdenes religiosas con vistas a la instalación de alguna de sus comunidades en el antiguo cenobio agustino de Nuestra Señora de Regla sito en la localidad gaditana de Chipiona en el marco del proceso de restauración de las órdenes religiosas vivido en España tras la supresión de las mismas, sobre todo con la llegada al trono español del rey Alfonso XII en 1875, proceso que se vio complicado por la instalación (...) en nuestro país de las comunidades religiosas expulsadas de Francia a partir de 1880. Se analiza especialmente el papel desempeñado por los franciscanos misioneros españoles y los monjes benedictinos franceses de las abadías de Solesmes y Ligugé. (shrink)

En este artículo se analizan las transformaciones producidas en el patrimonio artístico de la iglesia parroquial de la Purísima Concepción de Gilena entre los años 1874 y 1928 según los datos contenidos en varios inventarios de dicha iglesia realizados en ese tiempo.

Ampliación de un estudio anterior en la que se dan a conocer nuevas aportaciones acerca del devenir histórico de la iglesia parroquial de Gilena desde sus orígenes, en el siglo XVI, hasta el siglo XIX.

En este artículo se analiza un expediente conservado en el Archivo General del Arzobispado de Sevilla que trata acerca del intento de fundar una nueva congregación del Oratorio de San Felipe Neri en la ciudad de Écija el año 1749, fundación que finalmente no se llevó a cabo.

The topology of DNA duplexes changes during replication and also after deproteinization in vitro. Here we describe these changes and then discuss for the first time how the distribution of superhelical stress affects the DNA topology of replication intermediates, taking into account the progression of replication forks. The high processivity of Topo IV to relax the left‐handed (+) supercoiling that transiently accumulates ahead of the forks is not essential, since DNA gyrase and swiveling of the forks cooperate with Topo IV (...) to accomplish this task in vivo. We conclude that despite Topo IV has a lower processivity to unlink the right‐handed (+) crossings of pre‐catenanes and fully replicated catenanes, this is indeed its main role in vivo. This would explain why in the absence of Topo IV replication goes‐on, but fully replicated sister duplexes remain heavily catenated. (shrink)

Vaccines represent preventative interventions amenable to immunogenetic prediction of how human variability will influence their safety and efficacy. The genetic polymorphism among individuals within any population can render possible that the immunity elicited by a vaccine is variable in length and strength. The same immune challenge (virus and/or vaccine) could provoke partial, complete or even failed protection for some individuals treated under the same conditions. We review genetic variants and mechanistic relationships among chemokines, chemokine receptors, interleukins, interferons, interferon receptors, toll‐like (...) receptors, histocompatibility antigens, various immunoglobulins and major histocompatibility complex antigens. These are the targets for variation among macrophages, dendritic cells, natural killer cells, T‐ and B‐lymphocytes, and complement. The technology platforms (mRNA, viral vectors, proteins) utilized to produce vaccines against SARS‐CoV‐2 infections may each trigger genetically distinct immune reactogenic profiles. With DNA biobanking and immunoprofiling of recipients, global COVID‐19 vaccinations could launch a new era of personalized healthcare. (shrink)

The objectives of the present study were to adapt a grief intervention program to family caregivers of patients with dementia, and assess its effectiveness in improving the symptoms of grief and other health-related variables. The intervention was based on Shear and Bloom's grief intervention program, with the necessary adaptations for use in the grieving process for a family member's illness. A total of 52 family caregivers of individuals with dementia participated. They were evaluated using a battery of self-report measures assessing (...) grief, overload, resilience, post-traumatic growth, experiential avoidance, health-related quality of life, and benefits of care. The results suggest that the program is effective in improving grief symptoms, caregiver burden, resilience, post-traumatic growth, and quality of life of family caregivers. It is necessary to create and implement interventions targeting caregivers' feelings and manifestations of ambiguous grief, because there is a lack of programs providing an efficient solution for the mental and physical health of caregivers, and because of the human and socioeconomic cost involved in neglecting this group. (shrink)

El timbre general de los documentos implicados en el actual proceso de reforma educativa oscila entre la apología y el tecnocratismo, permaneciendo a la sombra de la discusión, por lo que al ámbito académico respecta, las más de las veces, el papel que la Universidad jugará como motor de la investigación y la innovación tecnológica en la dinámica competitiva de los grandes bloques capitalistas. Estos textos deben ser leídos en su contexto social, político y económico, así como confrontados a la (...) luz, o más bien a la oscuridad, de documentos de la Comisión Europea relativos a las políticas de convergencia y competitividad económica. Las siguientes... líneas acotan con gran precisión el contexto de la reforma: "Los poderes públicos, para asumir sus responsabilidades deben apoyar el desarrollo de los mercados del futuro y prever los ajustes en vez de sufrirlos. La Unión Europea debe situar mejor su capital científico y tecnológico al servicio de la competitividad industrial y de las necesidades de los mercados. Conviene prestar mayor atención a la difusión de los resultados de la innovación, su transferencia y su valorización por la industria y actualizar la distinción tradicional entre investigación fundamental, investigación precompetitiva e investigación aplicada para evitar lo que ha ocurrido en algunas ocasiones en el sentido de que la industria europea no siempre ha podido beneficiarse de todos los esfuerzos efectuados en materia de investigación" 1. Según creemos, el actual proceso de convergencia persigue la conversión de la educación superior en una mera función de la reproducción capitalista. The general tone of documents that relate to the actual education reform process oscillates between self-defense and technocratism. In academic circles, far from debate, the university is regarded as being the engine of investigation and the innovative technology that will be employed by large capitalist groups in their fields of dynamic competition. These texts should be read in their social, political and economic contexts and should be compared with the clarity or perhaps obscurity of European Commission papers written on convergence and economic competitiveness. We believe that the present convergence process is designed to promote further education as a mere tool to be used in capitalist reproduction. (shrink)

This work approaches views on the preservation of industrial housing heritage in Malaga, Spain, and the pressure caused by its recent urban renovation. The aims of the research include geographic space analysis and assessing how archaeological recording and archaeometry, specifically archaeometallurgy, can contribute to the preservation of information about structures and materials that continuously disappear from urban contexts. The results constitute an initial beginning to expand a comparative archaeological database for the city. The ideas and procedures presented here are expected (...) to provide some guidance for generating further research from urban, architectural, archaeological, and geographical perspectives. (shrink)

Aristotle’s soul is a first principle (an ‘efficient cause’) of every vital change in an animal, in the way that a craft is a cause of its product’s coming-to-be. We argue that the soul’s causal efficacy cannot therefore be reduced to the formal constitution of vital phenomena, or to discrete interventions into independently constituted processes, but involves the exercise of vital powers. This reading does better justice to Aristotle’s conception of craft as a rational productive disposition; and it captures the (...) soul’s continuous causal role as that which brings about all forms of vital change and underwrites their unity. (shrink)

El objetivo de este trabajo es dar a conocer algunas históricas que puedan ofrecer datos sobre la situación de los conventos de la provincia de Sevilla a finales del Antiguo Régimen. Para ello contamos con varios legajos conservados en el Archivo del Arzobispado de Sevilla y también la Crónica de dicha orden religiosa, del Padre Lucas de Montoya (Madrid 1619). Con todo ese material estamos en condiciones de aportar datos sobre tres momentos (1619, 1775 y 1821) que nos permitirán tener (...) una idea bastante aproximada sobre la evolución de esta orden religiosa en nuestra archidiócesis durante ese periodo. (shrink)

En este artículo damos a conocer ciertos documentos que nos aportan nuevos indicios para conocer cuál ha sido la trayectoria seguida por un cuadro atribuido a Zurbarán que perteneció a la Congregación del Oratorio de San Felipe Neri de Sevilla y que, con el tiempo, pasó amanos diferentes. Tal circunstancia nos sirve de pretexto para trazar, bien que someramente, un breve relato acerca de las vicisitudes en las que se vieron inmersos los patrimonios artísticos de los dos templos que sirvieron (...) de marco a las celebraciones religiosas de los oratorianos sevillanos, a saber, la desaparecida iglesia de San Felipe Neri y el templo del antiguo colegio carmelitano de San Alberto. (shrink)

This dissertation addresses the question of whether externalism and privileged access are compatible. I defend the view according to which they are, indeed, incompatible. However, this follows unproblematically from a distinction between two notions of mental content that I introduce and develop. My main suggestion is that a confusion between two notions of mental content is responsible for the view that the incompatibility of privileged access and externalism is problematic, since these are views about, strictly speaking, different varieties of mental (...) content. ;The discussion is divided into an introduction and four chapters. In the second chapter, I discuss the main argument for the position according to which externalism and privileged access are compatible. In the third chapter, I distinguish two kinds of mental content by using the two-dimensional semantics framework developed by David Kaplan, Robert Stalnaker and others. I then move to argue that externalism and privileged access are views about different sorts of content. Externalism is correct only when it is understood as a view about "objective content", essentially constituted by truth-conditions, whereas privileged access is correct only when it is understood as a view about "subjective content", a kind of "narrow" content essentially constituted by Stalnaker's "diagonal proposition". In the fourth chapter, I focus on privileged access and I offer an explanation of it. The main tenet of my account of privileged access is that our grounds for our first-order beliefs are the same as our grounds for the appropriate second-order beliefs. In the fifth chapter, I discuss the two main arguments for the position according to which externalism and privileged access are incompatible. By using the distinction regarding mental content drawn on chapter three, I argue that neither argument shows the incompatibility of externalism about objective content and privileged access about subjective content. Thus, I conclude that the incompatibility of privileged access and externalism is not problematic. (shrink)

The formula "being of beginning " is employed by Hegel to name the immediate non- determined being from which the beginning of science must take place. Beginning come together in it. Being and doing of beginning are one. To Hegel, this means that being is the only and factic response to the question about beginning. The being of beginning neither is nor represents itself by means of any principle, it is pure "determinetness". To Hegel, the task of depuration and action (...) of beginning constitutes the moment of consummation of philosophy. "Being", as a concept in itself, is set as pure sign void of signification. But in this lack of signification lies the "demand of signs". "Being of beginning" expresses being as pure sign. Lack and significance, considered up to now as negation and position of the being of beginning, are both consummated simultaneously and at the same time. Consummation of scepticism also carries nominalism with it. All words and representations may be emptied of significance and set to work in view of pure signification. But pure being may be considered, in the context of the Doctrine of Being, as the irreductible result of the proof of semiotic resistance carried out in the beginning. Scepticism consummates itself in beginning. "Being" is the only sign that signifies, even empty of significations; it is the only signifier in itself.La fórmula "ser del comienzo" es utilizada por Hegel para denominar al ser inmediato indeterminado a partir del cual debe ser hecho el comienzo de la ciencia. En ella convergen comienzo y ser. El ser y el hacer del comienzo son uno. Esto significa para Hegel que el ser es la única y fáctica respuesta a la pregunta por el comienzo. El ser del comienzo no es ni se representa mediante ningún principio, él es pura determinidad . La tarea de depuración y acción del comienzo constituye para Hegel el momento de consumación de la filosofía. "Ser" en tanto concepto en sí es puesto como signo puro vaciado de significación. Pero en esta carencia de significación radica la "demanda de signos". "Ser del comienzo" expresa al ser en tanto signo puro. Carencia y significación, considerados hasta aquí como negación y posición del ser del comienzo, se consuman ambos simultánea y conjuntamente. La consumación del escepticismo conlleva también del nominalismo. Todas las palabras o representaciones pueden ser vaciadas de significado y puestas en función de la pura significación. Pero el ser puro puede ser considerado, en el contexto de la Doctrina del ser, como el resultado irreductible de la prueba de resistencia semiótica efectuada por el comienzo. El escepticismo se consuma en el comienzo. "Ser" es el único signo que significa aún vacío de significados, es el único signo significante en sí. (shrink)

En el siguiente artículo analizamos las diferentes aportaciones que, desde Nietzsche y Husserl hasta los estudios de Freud, han servido para trazar una genealogía de la imagen. Ello nos permitirá examinar cuáles han sido los enfoques que se han ocupado de la imagen, los puntos de conexión entre diferentes teorías y los conflictos epistemológicos de cada posicionamiento.In the following paper we analyze the different contributions that, from Nietzsche and Husserl to Freud’s studies, have served to trace a genealogy of image. (...) This will allow us to examine what were the approaches that have dealt with the image, the connection points between different theories and epistemological conflicts of each position. (shrink)

El objetivo de este trabajo es presentar un documento escrito por un monje minimalista en 1818, lo que nos proporciona con nuevos datos sobre la situación de la Mínima monasterios pertenecientes a la provincia de Sevilla al final del Antiguo Régimen. Esto nos permitirá acercarnos a la situación de los Mínimos en nuestra archidiócesis durante ese periodo. Ese documento es hoy parte de los fondos documentales conservados en el Archivo General de la Arzobispado de Sevilla.

The questions inherent to the relationship between time and freedom reach their maturity in the works of Hegel and Schelling. In this article, we will attend particularly to the latter since the way opened by his "Investigations on the essence of human freedom" derives quite clearly into the successive attempts of exposition of a system of time in the "Ages of the World" and in the Lessons of München . Following Schelling's development, then, we will try to understand why in (...) the post-Kantian idealism the search for a philosophy of the spirit as a system of freedom leads to treat "time" not only as an a priori intuition of sensibility but as an inherent determination of the absolute, and in that sense, why in Schelling's thought system of freedom and system of time are equivalent to the exposition of the absolute.Las cuestiones inherentes a la relación entre tiempo y libertad alcanzan su madurez en las obras de Hegel y Schelling. En el presente artículo atenderemos de manera particular a este último, ya que el camino abierto por sus Investigaciones sobre la esencia de la libertad humana deriva con cierta claridad en los sucesivos intentos de exposición de un sistema del tiempo en las Edades del mundo y en las Lecciones de München . Siguiendo el desarrollo de Schelling, pues, intentaremos comprender por qué en el idealismo postkantiano la búsqueda de una filosofía del espíritu como sistema de la libertad conduce a tratar el "tiempo" ya no sólo como una intuición a priori de la sensibilidad sino como una determinación inherente al absoluto, y, en tal sentido, por qué en el pensamiento de Schelling sistema de la libertad y sistema del tiempo equivalen a la exposición del absoluto. (shrink)

The aim of this study was to evaluate the neuromuscular response to an agility and repeated sprint ability test according to the level of competition in futsal players. A total of 33 players from two elite teams and one amateur team participated in the study. The participants completed an agility t-test, a 30 m-speed test, and a RSA test. A countermovement jump test and a tensiomyography test of the rectus femoris and biceps femoris of both legs were carried out before (...) and after the tests. RSA test revealed better sprint times in elite players compared to amateurs in the seven bouts, as well as in the 30 m sprint and in the agility test. In conclusion, elite players showed greater performance in the RSA test, in the 30 m tests and in the agility test compared to amateur players. The contractile properties were not a key factor in the RSA performance of the futsal players. (shrink)

Unfounded—conspiracy and health—beliefs about COVID-19 have accompanied the pandemic worldwide. Here, we examined cross-nationally the structure and correlates of these beliefs with an 8-item scale, using a multigroup confirmatory factor analysis. We obtained a two-factor model of unfounded (conspiracy and health) beliefs with good internal structure (average CFI = 0.98, RMSEA = 0.05, SRMR = 0.04), but a high correlation between the two factors (average latent factor correlation = 0.57). This model was replicable across 50 countries (total N = 13,579), (...) as evidenced by metric invariance between countries (CFI = 0.96, RMSEA = 0.06, SRMS = 0.07) as well as scalar invariance across genders (CFI = 0.98, RMSEA = 0.04, SRMS = 0.03) and educational levels (CFI = 0.98, RMSEA = 0.04, SRMS = 0.03). Also, lower levels of education, more fear of COVID-19, and more cynicism were weakly associated with stronger conspiracy and health beliefs. The study contributes to knowledge about the structure of unfounded beliefs, and reveals the potential relevance of affective (i.e., fear of COVID-19) and cognitive (i.e., cynicism) factors along with demographics, in endorsing such beliefs. In summary, we obtained cross-cultural evidence for the distinctiveness of unfounded conspiracy and health beliefs about COVID-19 in terms of their structure and correlates. (shrink)

The global market for biologics and biosimilar pharmaceutical products is experiencing rapid expansion, primarily driven by the continuous discovery of new molecules. However, information regarding Latin America’s biological market remains limited.

Unfounded—conspiracy and health—beliefs about COVID-19 have accompanied the pandemic worldwide. Here, we examined cross-nationally the structure and correlates of these beliefs with an 8-item scale, using a multigroup confirmatory factor analysis. We obtained a two-factor model of unfounded (conspiracy and health) beliefs with good internal structure (average CFI = 0.98, RMSEA = 0.05, SRMR = 0.04), but a high correlation between the two factors (average latent factor correlation = 0.57). This model was replicable across 50 countries (total N = 13,579), (...) as evidenced by metric invariance between countries (CFI = 0.96, RMSEA = 0.06, SRMS = 0.07) as well as scalar invariance across genders (CFI = 0.98, RMSEA = 0.04, SRMS = 0.03) and educational levels (CFI = 0.98, RMSEA = 0.04, SRMS = 0.03). Also, lower levels of education, more fear of COVID-19, and more cynicism were weakly associated with stronger conspiracy and health beliefs. The study contributes to knowledge about the structure of unfounded beliefs, and reveals the potential relevance of affective (i.e., fear of COVID-19) and cognitive (i.e., cynicism) factors along with demographics, in endorsing such beliefs. In summary, we obtained cross-cultural evidence for the distinctiveness of unfounded conspiracy and health beliefs about COVID-19 in terms of their structure and correlates. (shrink)

Book review: Vargas, Miguel Ángel Fernández. Performance Epistemology. Foundations andApplications. Oxford: Oxford Un. Press, 2016.